ELISA Kit for Human Phorbol-12-myristate-13-acetate-induced protein 1

Mfr.No.	E13268h
Alternative Names	Immediate-early-response protein APR ; Protein Noxa ; NOXA
Categories	Elisa
Function	Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
Specificity	Natural and recombinant Human Phorbol-12-myristate-13-acetate-induced protein 1
Subcellular Location	Mitochondrion
Detection Range	78-5000pg/mL
Entryname	APR_HUMAN
Method Type	Sandwich
Platform	PF15150
Protein Name	Phorbol-12-myristate-13-acetate-induced protein 1
Sensitivity	31pg/ml
Sequence	50: MPGKKARKNA ; QPSPARAPAG ; PAGTAGTARD ; QAGFAIGMQL ; RFTRGKKLLS ; 100: SSLSSSPLAL ; PRGHEEQVQV ; AGSRVCYSTQ ; EIWRQTELPA ; ETSESDIQTL ; 136: LLRNLTASKT ; CMRGLLQKSF ; LRRCTFHQFE ; ERLHCN
Sequence Length	136
String	Q13794
Sub Unit	Interacts with MCL1 and BAX.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13800847	E13268h	96T	$736		Add to Cart