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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Caspase-1

SKU : BHE13801490

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1592h
Alternative Names	Interleukin-1 beta convertase ; IL-1BC ; Interleukin-1 beta-converting enzyme ; ICE ; p45 ; IL1BC ; IL1BCE
Categories	Elisa
Function	Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
Specificity	Natural and recombinant Human Caspase-1
Subcellular Location	Cytoplasm
Detection Range	15.6-1000pg/mL
Entryname	CASP1_HUMAN
Method Type	Sandwich
Platform	PF00619
Protein Name	Caspase-1
Sensitivity	10pg/mL
Sequence	50: MADKVLKEKR ; KLFIRSMGEG ; TINGLLDELL ; QTRVLNKEEM ; EKVKRENATV ; 100: MDKTRALIDS ; VIPKGAQACQ ; ICITYICEED ; SYLAGTLGLS ; ADQTSGNYLN ; 150: MQDSQGVLSS ; FPAPQAVQDN ; PAMPTSSGSE ; GNVKLCSLEE ; AQRIWKQKSA ; 200: EIYPIMDKSS ; RTRLALIICN ; EEFDSIPRRT ; GAEVDITGMT ; MLLQNLGYSV ; 250: DVKKNLTASD ; MTTELEAFAH ; RPEHKTSDST ; FLVFMSHGIR ; EGICGKKHSE ; 300: QVPDILQLNA ; IFNMLNTKNC ; PSLKDKPKVI ; IIQACRGDSP ; GVVWFKDSVG ; 350: VSGNLSLPTT ; EEFEDDAIKK ; AHIEKDFIAF ; CSSTPDNVSW ; RHPTMGSVFI ; 400: GRLIEHMQEY ; ACSCDVEEIF ; RKVRFSFEQP ; DGRAQMPTTE ; RVTLTRCFYL ; 404: FPGH
Sequence Length	404
String	P29466
Sub Unit	Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 20 kDa (p20) and a 10 kDa (p10) subunit. The p20 subunit can also form a heterodimer with the epsilon isoform which then has an inhibitory effect. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and NALP2 and whose function would be the activation of proinflammatory caspases. Interacts with CARD17/INCA and CARD18.

Uniprot	P29466
Gene Name	CASP1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:834
Unigene	Hs.2490

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SKU	Supplier No.	Size	Your price	Quantity
BHE13801490	E1592h	96T	$536		Add to Cart

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