Serine-type endopeptidase involved in atrial natriuretic peptide hormone processing. Converts through proteolytic cleavage the non-functional propeptide NPPA/ANP into the active hormone which promotes natriuresis, diuresis, and vasodilatation. May also process pro-NPPB the B-type natriuretic peptide.
Specificity
Natural and recombinant Human Atrial natriuretic peptide-converting enzyme
Subcellular Location
Cell membrane Single-pass type II membrane protein