Rat Multidrug Resistance-associated Protein 1

Mfr.No.

E2156Ra

Alternative Names

ABCC 1;ABCC1;ATP-binding cassette sub-family C member 1;Glutathione-S-conjugate-translocating ATPase ABCC1;Leukotriene C(4 transporter;LTC4 transporter;Multidrug resistance-associated protein 1

Reactivity

Rat

Detection Range

10-2000ng/L

Sample Type

Serum, Cell culture supernatants, Plasma

Assay Type

Sandwich

Assay Duration

1h 30m

Molecular Weight

171493

Kit Components

Components	Quantity
Pre-coated ELISA Plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Sensitivity

5.45ng/L

Background

Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export. Hydrolyzes ATP with low efficiency (PubMed: 15129170). Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation (PubMed: 17050692). Participates in inflammatory response by allowing export of leukotriene C4 from leukotriene C4-synthezing cells (By similarity).

Gene ID	24565
UniProt ID	Q8CG09
Antigen	ABCC1

Research Area

Signal Transduction; Cancer; Cardiovascular; Metabolism

Protocol

These standard curves of E2156Ra are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
1200ng/L	2.352	2.384	2.332
	2.415
600ng/L	1.407	1.434	1.383
	1.461
300ng/L	0.71	0.711	0.66
	0.712
150ng/L	0.518	0.494	0.443
	0.47
75ng/L	0.303	0.316	0.264
	0.328
0ng/L	0.052	0.052	0
	0.051

Precision

We measured random samples of E2156Ra within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	731.6	20.57	2.8
Intra-Assay	2	18	425.2	25.79	6.1
Intra-Assay	3	18	273.1	19.89	7.3

Storage	2-8°C

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SKU	Supplier No.	Size	Your price	Quantity
BHE12113288	E2156Ra	48T	$320		Add to Cart
BHE12113288	E2156Ra	96T	$458		Add to Cart

Rat Multidrug Resistance-associated Protein 1 - ABCC1 ELISA Kit

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