Mouse Receptor Tyrosine-protein Kinase ERBB-3

Mfr.No.

E2418Mo

Sensitivity

0.054ng/mL

Detection Range

0.1-40ng/mL

Reactivity

Mouse

Assay Duration

1h 30m

Assay Type

Sandwich

Alternative Names

C76256;Erbb;Erbb-;ERBB3;Erbb-3;Glial growth factor receptor;HER;Her3;Proto-oncogene-like protein c-ErbB-3;Receptor tyrosine-protein kinase erbB-3

Molecular Weight

147613

Kit Components

Components	Quantity
Pre-coated ELISA plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Precision

We measured random samples of E2418Mo within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	18.67	0.59	3.17
Intra-Assay	2	18	4.34	0.24	5.46
Intra-Assay	3	18	9.6	0.55	5.71

Background

Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5. Involved in the regulation of myeloid cell differentiation.

Protocol

These standard curves of E2418Mo are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
24ng/mL	2.233	2.183	2.141
	2.133
12ng/mL	1.257	1.247	1.206
	1.238
6ng/mL	0.647	0.725	0.683
	0.803
3ng/mL	0.449	0.439	0.397
	0.428
1.5ng/mL	0.246	0.223	0.181
	0.2
0ng/mL	0.033	0.042	0
	0.05

Gene ID	13867
UniProt ID	Q61526

Research Area	Signal Transduction; Cancer

Storage	2-8°C

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SKU	Supplier No.	Size	Your price	Quantity
BHE12110229	E2418Mo	48T	$320		Add to Cart
BHE12110229	E2418Mo	96T	$458		Add to Cart

Mouse Receptor Tyrosine-protein Kinase ERBB-3 - ERBB3 ELISA Kit

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