Loading ....
BHE12109076
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Continuing the saving: $50 Off All ELISA Kits Offer Extended!
Contact us to order
Tel
+1 866.986.9598
Bioassay Technology Laboratory
view supplier detailsCredit card payments now incur a 3% fee.
