Mouse Bone Morphogenetic Protein Receptor Type-1B

Mfr.No.

E1888Mo

Sensitivity

0.013ng/mL

Detection Range

0.05-20ng/mL

Reactivity

Mouse

Assay Duration

1h 30m

Assay Type

Sandwich

Alternative Names

Activin receptor-like kinase 6;ALK-6;BMP type-1B receptor;BMPR 1B;BMPR1B;BMPR-1B;Bone morphogenetic protein receptor type-1B;CD antigen CDw293;Serine/threonine-protein kinase receptor R6;SKR6

Molecular Weight

56944

Kit Components

Components	Quantity
Pre-coated ELISA Plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Precision

We measured random samples of E1888Mo within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	3.3	0.14	4.1
Intra-Assay	2	18	6.8	0.33	4.9
Intra-Assay	3	18	9.9	0.39	3.9

Background

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1. Receptor for GDF5 (PubMed: 26105076, PubMed: 19229295). Positively regulates chondrocyte differentiation through GDF5 interaction (PubMed: 24098149).

Protocol

These standard curves of E1888Mo are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
12ng/mL	1.957	1.89	1.858
	1.823
6ng/mL	1.074	1.048	1.015
	1.021
3ng/mL	0.626	0.547	0.515
	0.469
1.5ng/mL	0.214	0.244	0.212
	0.275
0.75ng/mL	0.089	0.078	0.046
	0.068
0ng/mL	0.027	0.032	0
	0.038

Gene ID	12167
UniProt ID	P36898

Research Area	Others

Storage	2-8°C

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SKU	Supplier No.	Size	Your price	Quantity
BHE12109700	E1888Mo	48T	$320		Add to Cart
BHE12109700	E1888Mo	96T	$458		Add to Cart

Mouse Bone Morphogenetic Protein Receptor Type-1B - BMPR1B ELISA Kit

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