BHE13703825
MIOS (Meiosis Regulator For Oocyte Development) is a Protein Coding gene. Among its related pathways are mTOR signaling pathway (KEGG) and PI3K / Akt Signaling. As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. It is negatively regulated by the upstream amino acid sensors SESN2 and GATSL3.
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