Human Tumor Necrosis Factor Receptor Superfamily Member 1B

Mfr.No.

E6846Hu

Alternative Names

CD antigen CD120b;Etanercept;p75;p80 TNF-alpha receptor;TBP-2;TBPII;TNF-R2;TNFR-II;TNF-RII;TNFRSF 1B;TNFRSF1B;Tumor necrosis factor receptor 2;Tumor necrosis factor receptor superfamily member 1B;Tumor necrosis factor receptor superfamily member 1b, membrane form;Tumor necrosis factor receptor type II;Tumor necrosis factor-binding protein 2

Reactivity

Human

Detection Range

20-3800ng/L

Sample Type

Serum, Plasma, Cell culture supernatants

Assay Type

Sandwich

Assay Duration

1h 30m

Molecular Weight

48291

Kit Components

Components	Quantity
Pre-coated ELISA Plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Sensitivity

10.98ng/L

Background

Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.

Gene ID	7133
UniProt ID	P20333
Antigen	TNFRSF1B

Research Area

Signal Transduction

Protocol

These standard curves of E6846Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
2000ng/L	2.336	2.217	2.163
	2.097
1000ng/L	1.235	1.257	1.204
	1.279
500ng/L	0.829	0.857	0.803
	0.885
250ng/L	0.556	0.533	0.48
	0.51
125ng/L	0.272	0.258	0.205
	0.244
0ng/L	0.061	0.053	0
	0.046

Precision

We measured random samples of E6846Hu within the same batch/lot to ensure the consistency of the kits' performances.

Storage	2-8°C

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SKU	Supplier No.	Size	Your price	Quantity
BHE12115579	E6846Hu	48T	$320		Add to Cart
BHE12115579	E6846Hu	96T	$458		Add to Cart

Human Tumor Necrosis Factor Receptor Superfamily Member 1B - TNFRSF1B ELISA Kit

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