TM4SF20, Belongs to the L6 tetraspanin family, Members of the L6 family of membrane proteins, a branch of the tetraspanin superfamily, are overexpressed in tumor cells from many types of cancers. However, direct evidence of their oncogenic activity has not been previously shown.
this gene is expressed at low level, only 16.6% of the average gene in this release.The gene contains 4 different gt-ag introns. Transcription produces one mRNA. There are 3 validated alternative polyadenylation sites. The spliced mRNA putatively encodes a good protein, containing L6 membrane domain, some transmembrane domains, apparently vertebrate specific Proteins are expected to localize in various compartments.
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