Human Telomeric Repeat-binding Factor 1

Mfr.No.

E6257Hu

Sensitivity

9.63ng/L

Detection Range

20-3800ng/L

Reactivity

Human

Assay Duration

1h 30m

Assay Type

Sandwich

Alternative Names

NIMA-interacting protein 2;Telomeric protein Pin2/TRF1;Telomeric repeat-binding factor 1;TERF 1;TERF1;TTAGGG repeat-binding factor 1

Molecular Weight

50246

Kit Components

Components	Quantity
Pre-coated ELISA Plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Precision

We measured random samples of E6257Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	1306.1	51.83	4
Intra-Assay	2	18	573	34.15	6
Intra-Assay	3	18	347.7	26.61	7.7

Background

Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.

Protocol

These standard curves of E6257Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
2000ng/L	2.022	2.015	1.959
	2.008
1000ng/L	1.296	1.36	1.304
	1.424
500ng/L	0.773	0.796	0.74
	0.818
250ng/L	0.542	0.509	0.453
	0.475
125ng/L	0.261	0.257	0.202
	0.253
0ng/L	0.052	0.056	0
	0.06

Gene ID	7013
UniProt ID	P54274

Research Area	Epigenetics and Nuclear Signaling

Storage	2-8°C

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SKU	Supplier No.	Size	Your price	Quantity
BHE12107619	E6257Hu	48T	$320		Add to Cart
BHE12107619	E6257Hu	96T	$458		Add to Cart

Human Telomeric Repeat-binding Factor 1 - TERF1 ELISA Kit

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