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Human Synaptotagmin-13 (SYT13) ELISA Kit

BHE13702645

Unlike most of the synaptotagmins, SYT13 does not have an N-terminal transmembrane region. Its C2 domains are lacking almost all the residues involved in Ca2+ binding. It is highly expressed in brain and also detectable at lower levels in non-neuronal tissues. SYT13 can suppress liver tumour cells and this function may be mediated through pathways implicated in mesenchymal to epithelial transition. It also affects insulin secretion.

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