Human Sorbin and Sh3 Domain-containing Protein 2

Mfr.No.

E6204Hu

Alternative Names

Arg/Abl-interacting protein 2;Arg-binding protein 2;ARGBP2;PRO0618;Sorbin;Sorbin and SH3 domain-containing protein 2;SORBS2

Reactivity

Human

Detection Range

20-4500ng/L

Sample Type

Serum, Plasma, Cell culture supernatants

Assay Type

Sandwich

Assay Duration

1h 30m

Molecular Weight

124108

Kit Components

Components	Quantity
Pre-coated ELISA plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Sensitivity

9.81ng/L

Background

Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1. May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12 (PubMed:18559503). Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.

Gene ID	8470
UniProt ID	O94875
Antigen	SORBS2

Research Area

Signal Transduction

Protocol

These standard curves of E6204Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
2400ng/L	2.155	2.069	2.033
	1.983
1200ng/L	1.502	1.51	1.474
	1.519
600ng/L	0.663	0.667	0.63
	0.671
300ng/L	0.314	0.387	0.351
	0.461
150ng/L	0.203	0.16	0.124
	0.118
0ng/L	0.036	0.037	0
	0.037

Precision

We measured random samples of E6204Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	328.58	11.18	3.4
Intra-Assay	2	18	974.83	31.46	3.23
Intra-Assay	3	18	878.59	36.04	4.1

Storage	2-8°C

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SKU	Supplier No.	Size	Your price	Quantity
BHE12107566	E6204Hu	48T	$320		Add to Cart
BHE12107566	E6204Hu	96T	$458		Add to Cart

Human Sorbin and Sh3 Domain-containing Protein 2 - SORBS2 ELISA Kit

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