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Home / ELISA Kit

Human Rho Guanine Nucleotide Exchange Factor 4 - ARHGEF4 ELISA Kit

BHE12104766

Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.

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Gene ID 50649
UniProt ID Q9NR80
Antigen ARHGEF4
Research Area Others
Protocol These standard curves of E3237Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
640ng/L 2.63 2.643 2.599
2.657
320ng/L 1.371 1.384 1.34
1.398
160ng/L 0.866 0.818 0.773
0.77
80ng/L 0.532 0.481 0.436
0.43
40ng/L 0.258 0.257 0.212
0.256
0ng/L 0.06 0.045 0
0.029
Precision We measured random samples of E3237Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 133.18 7.61 5.71
Intra-Assay 2 18 332.05 10.07 3.03
Intra-Assay 3 18 244.38 13.11 5.37
Storage 2-8°C
SKU Supplier No. Size Your price Quantity
BHE12104766 E3237Hu 48T $320
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BHE12104766 E3237Hu 96T $458
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