BHE13703287
Prostaglandin F2-alpha receptor encoded by PTGFR is member of the G-protein coupled receptor family. Prostaglandin F2-alpha receptor is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for PTGFR.
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