Human Low Affinity Immunoglobulin Gamma Fc Region Receptor 3-B

Mfr.No.

E5598Hu

Sensitivity

0.29ng/mL

Detection Range

0.5-200ng/mL

Reactivity

Human

Assay Duration

1h 30m

Assay Type

Sandwich

Alternative Names

CD antigen CD16b;CD16;CD16A;CD16b;FCG3;Fc-gamma RIII;Fc-gamma RIIIb;Fc-gamma RIII-beta;FCGR3;FCGR3A;FCGR3B;FcR10;FcR-10;FCRIII;FCRIIIb;IGFR3;IgG Fc receptor III-1;Low affinity immunoglobulin gamma Fc region receptor III-B

Molecular Weight

26216

Kit Components

Components	Quantity
Pre-coated ELISA plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Precision

We measured random samples of E5598Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	24.46	1.29	5.28
Intra-Assay	2	18	49.48	2.88	5.82
Intra-Assay	3	18	90.19	2.94	3.26

Background

Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.

Protocol

These standard curves of E5598Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
120ng/mL	2.216	2.308	2.258
	2.399
60ng/mL	1.285	1.312	1.262
	1.339
30ng/mL	0.812	0.847	0.797
	0.883
15ng/mL	0.423	0.431	0.381
	0.439
7.5ng/mL	0.319	0.281	0.231
	0.243
0ng/mL	0.051	0.05	0
	0.05

Gene ID	2215
UniProt ID	O75015

Research Area	Immunology

Storage	2-8°C

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SKU	Supplier No.	Size	Your price	Quantity
BHE12106960	E5598Hu	48T	$320		Add to Cart
BHE12106960	E5598Hu	96T	$458		Add to Cart

Human Low Affinity Immunoglobulin Gamma Fc Region Receptor 3-B - FCGR3B ELISA Kit

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