Human Kv Channel-interacting Protein 4

Mfr.No.

E3830Hu

Description

This sandwich kit is for the accurate quantitative detection of human Kv Channel-interacting Protein 4 (also known as KCNIP4) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates.

Alternative Names

A-type potassium Channel modulatory protein 4;CALP;Calsenilin-like protein;KCHIP4;KCNIP4;Kv Channel-interacting protein 4;Potassium Channel-interacting protein 4

Reactivity

Human

Detection Range

0.05-30ng/ml

Sample Type

Serum, Plasma, Cell culture supernatants

Assay Type

Sandwich

Assay Duration

1h 30m

Molecular Weight

28729

Kit Components

Components	Quantity
Pre-coated ELISA plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Sensitivity

0.024ng/ml

Background

Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates KCND2 channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner (PubMed:11847232, PubMed:18957440, PubMed:23576435). Modulates KCND3/Kv4.3 currents (PubMed:23576435). Isoform 4 does not increase KCND2 expression at the cell membrane (PubMed:18957440). Isoform 4 retains KCND3 in the endoplasmic reticulum and negatively regulates its expression at the cell membrane.

Gene ID	80333
UniProt ID	Q6PIL6
Antigen	KCNIP4

Research Area

Neuroscience

Protocol

These standard curves of E3830Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
20ng/ml	2.265	2.298	2.239
	2.331
10ng/ml	1.169	1.181	1.122
	1.193
5ng/ml	0.854	0.752	0.693
	0.651
2.5ng/ml	0.46	0.49	0.431
	0.521
1.25ng/ml	0.247	0.238	0.179
	0.228
0ng/ml	0.059	0.059	0
	0.059

Precision

We measured random samples of E3830Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	15.35	0.42	2.72
Intra-Assay	2	18	5.36	0.29	5.43
Intra-Assay	3	18	3.05	0.18	5.83

Storage	2-8°C

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SKU	Supplier No.	Size	Your price	Quantity
BHE12105275	E3830Hu	48T	$320		Add to Cart
BHE12105275	E3830Hu	96T	$458		Add to Cart

Human Kv Channel-interacting Protein 4 - KCNIP4 ELISA Kit

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