Human Kidney Injury Molecule 1

Mfr.No.

E1099Hu

Sensitivity

0.01ng/ml

Detection Range

0.05-10ng/ml

Reactivity

Human

Assay Duration

1h 30m

Assay Type

Sandwich

Description

This sandwich kit is for the accurate quantitative detection of Kidney injury molecule 1 (also known as KIM-1) in serum, plasma, cell culture supeates, cell lysates, tissue homogenates.

Alternative Names

CD antigen CD365;HAVCR 1;HAVCR1;HAVcr-1;Hepatitis A virus cellular receptor 1;Kidney injury molecule 1;KIM-1;T-cell immunoglobulin and mucin domain-containing protein 1;T-cell immunoglobulin mucin receptor 1;T-cell membrane protein 1;TIM;TIM-1;TIMD-1;

Molecular Weight

39250

Kit Components

Components	Quantity
Pre-coated ELISA Plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Precision

We measured random samples of E1099Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	1	0.04	4.5
Intra-Assay	2	18	1.9	0.07	3.7
Intra-Assay	3	18	0.7	0.03	4.9

Background

May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4 (By similarity). May play a role in kidney injury and repair. (Microbial infection) Acts as a receptor for Hepatitis A virus. (Microbial infection) Acts as a receptor for Ebolavirus and Marburg virus by binding exposed phosphatidyl-serine at the surface of virion membrane (PubMed: 21536871). Serves as a dual receptor for Ebolavirus by also interacting with envelope glycoprotein GP (PubMed: 26487564). (Microbial infection) Acts as a receptor for Dengue virus by binding exposed phosphatidyl-serine at the surface of virion membrane. (Microbial infection) Acts as a receptor for Zika virus by binding to envelope protein E.

Protocol

These standard curves of E1099Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
6.4ng/ml	2.071	2.212	2.146
	2.353
3.2ng/ml	1.933	1.842	1.776
	1.751
1.6ng/ml	1.179	1.153	1.088
	1.127
0.8ng/ml	0.737	0.689	0.623
	0.641
0.4ng/ml	0.413	0.4	0.334
	0.387
0ng/ml	0.066	0.066	0
	0.065

Gene ID	26762
UniProt ID	Q96D42

Research Area	Immunology

Storage	2-8°C

Reference	Efficacy of multiple Biomarkers: NGAL, KIM1, Cystatin C and IL18 in predicting pregnancy related acute kidney injury Joual: Pak J Med Sci. 2023 Jan-Feb;39(1):34-40.

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SKU	Supplier No.	Size	Your price	Quantity
BHE12102749	E1099Hu	48T	$320		Add to Cart
BHE12102749	E1099Hu	96T	$458		Add to Cart

Human Kidney Injury Molecule 1 - KIM-1 ELISA Kit

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