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Human Interleukin 1beta - IL-1B ELISA Kit

BHE12101878

Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells (PubMed: 10653850). Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6 (PubMed: 12794819).

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Gene ID 3553
UniProt ID P01584
Research Area Immunology; Microbiology; Cardiovascular; Metabolism
Storage 2-8°C
Reference
Different spexin level in obese vs normal weight children and its relationship with obesity related risk factors
Journal: Nutr Metab Cardiovasc Dis. 2020 Apr 12;30(4):674-682
The Potential Predictive Role of Tumour Necrosis Factor-?, Interleukin-1?, and Monocyte Chemoattractant Protein-1 for COVID-19 Patients Survival
Journal: Infect Drug Resist. 2022 Mar 4;15:821-829
Evaluation of periodontal status and cytokine response in children with familial Mediterranean fever or systemic juvenile idiopathic arthritis
Journal: Clin Oral Investig. 2022 Oct 5
The Relationship between Serum Concentrations of Pro- and Anti-Inflammatory Cytokines and Nutritional Status in Patients with Traumatic Head Injury in the Intensive Care Unit
Journal: Medicina (Kaunas). 2019 Aug 15;55(8):486
Correlation between serum pro inflammatory cytokines and clinical scores of knee osteoarthritic patients using resveratrol as a supplementary therapy with meloxicam
Journal: Indian J Pharmacol. 2021 Jul-Aug;53(4):270-277.
The Potential Predictive Role of Tumour Necrosis Factor-?, Interleukin-1?, and Monocyte Chemoattractant Protein-1 for COVID-19 Patients Survival
Journal: Infect Drug Resist. 2022 Mar 4;15:821-829.
Evaluation of periodontal status and cytokine response in children with familial Mediterranean fever or systemic juvenile idiopathic arthritis
Journal: Clin Oral Investig. 2023 Mar;27(3):1159-1166.
The Relationship between Serum Concentrations of Pro- and Anti-Inflammatory Cytokines and Nutritional Status in Patients with Traumatic Head Injury in the Intensive Care Unit
Journal: Medicina (Kaunas). 2019 Aug 15;55(8):486.
Effect of high amylose resistant starch (HAM?RS2) supplementation on biomarkers of inflammation and oxidative stress in hemodialysis patients: a randomized clinical trial
Journal: Hemodial Int. 2018 Oct;22(4):492-500.
Correlation Between IL-8, C-Reactive Proteins (CRP) and Neutrophil to Lymphocyte Ratio (NLR) as Predictor of Mortality in COVID-19 Patients with Diabetes Mellitus Comorbidity
Journal: Int J Gen Med. 2023 Jun 8;16:2349-2354.
Effects of autologous leukocyte-platelet rich fibrin (L-PRF) on the rate of maxillary canine retraction and various biomarkers in gingival crevicular fluid (GCF): A split mouth randomized controlled trial
Journal: Int Orthod. 2022 Dec;20(4):100681.
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BHE12101878 E0143Hu 48T $320
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