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BHE12106871
High-affinity receptor for interleukin-15 (PubMed: 8530383). Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells (By similarity). In neutrophils, binds and activates kinase SYK in response to IL15 stimulation (PubMed: 15123770). In neutrophils, required for IL15-induced phagocytosis in a SYK-dependent manner (PubMed: 15123770). Expression of different isoforms may alter or interfere with signal transduction (PubMed: 10480910). [Isoform 5]: Does not bind IL15. [Isoform 6]: Does not bind IL15. [Isoform 7]: Does not bind IL15. [Isoform 8]: Does not bind IL15.
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