Human Intercellular Adhesion Molecule 1

Mfr.No.

E0212Hu

Alternative Names

CD antigen CD54;ICAM 1;ICAM1;ICAM-1;Intercellular adhesion molecule 1;Major group rhinovirus receptor

Reactivity

Human

Detection Range

20-6000ng/L

Sample Type

Serum, Plasma, Cell culture supernatants

Assay Type

Sandwich

Assay Duration

1h 30m

Molecular Weight

57825

Kit Components

Components	Quantity
Pre-coated ELISA Plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Sensitivity

9.56ng/L

Background

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. (Microbial infection) Acts as a receptor for major receptor group rhinovirus A-B capsid proteins. (Microbial infection) Acts as a receptor for Coxsackievirus A21 capsid proteins. (Microbial infection) Upon Kaposi's sarcoma-associated herpesvirus/HHV-8 infection, is degraded by viral E3 ubiquitin ligase MIR2, presumably to prevent lysis of infected cells by cytotoxic T-lymphocytes and NK cell.

Gene ID	3383
UniProt ID	P05362
Antigen	ICAM1

Research Area

Immunology

Protocol

These standard curves of E0212Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
3200ng/L	1.884	1.86	1.826
	1.836
1600ng/L	1.005	1.044	1.01
	1.083
800ng/L	0.585	0.558	0.525
	0.532
400ng/L	0.246	0.253	0.219
	0.26
200ng/L	0.076	0.09	0.056
	0.104
0ng/L	0.028	0.034	0
	0.04

Precision

We measured random samples of E0212Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	938.6	46.7	5
Intra-Assay	2	18	2744.9	110.85	4
Intra-Assay	3	18	1291.6	65.27	5.1

Storage	2-8°C

Reference	The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients Journal: Gynecol Endocrinol.2.28.2021 Jan;37(1):26-30. Association between Vascular Endothelial Markers and Carotid Intima-Media Thickness in Children and Adolescents with Type 1 Diabetes Mellitus Journal: J Clin Diagn Res. 2017 Sep;11(9):SC01-SC05.

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SKU	Supplier No.	Size	Your price	Quantity
BHE12101932	E0212Hu	96T	$458		Add to Cart
BHE12101932	E0212Hu	48T	$320		Add to Cart

Human Intercellular Adhesion Molecule 1 - ICAM-1 ELISA Kit

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