Human Insulin-like Growth Factor 2 MRNA-binding Protein 3

Mfr.No.

E5474Hu

Sensitivity

9.87ng/L

Detection Range

20-4500ng/L

Reactivity

Human

Assay Duration

1h 30m

Assay Type

Sandwich

Alternative Names

hKOC;IGF2 mRNA-binding protein 3;IGF2BP3;IGF-II mRNA-binding protein 3;IMP-3;Insulin-like growth factor 2 mRNA-binding protein 3;KH domain-containing protein overexpressed in cancer;VICKZ family member 3

Molecular Weight

63705

Kit Components

Components	Quantity
Pre-coated ELISA Plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Precision

We measured random samples of E5474Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	781.3	31.87	4.1
Intra-Assay	2	18	1952	68.07	3.5
Intra-Assay	3	18	1181.3	57.89	4.9

Background

RNA-binding factor that may recruit target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5'-UTR of the Insulin-like growth factor 2 (IGF2) mRNAs.

Protocol

These standard curves of E5474Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
2400ng/L	2.114	1.972	1.932
	1.831
1200ng/L	1.156	1.139	1.098
	1.121
600ng/L	0.455	0.517	0.476
	0.578
300ng/L	0.264	0.239	0.198
	0.215
150ng/L	0.081	0.102	0.061
	0.123
0ng/L	0.026	0.041	0
	0.056

Gene ID	10643
UniProt ID	O00425

Research Area	Epigenetics and Nuclear Signaling

Storage	2-8°C

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SKU	Supplier No.	Size	Your price	Quantity
BHE12106836	E5474Hu	48T	$320		Add to Cart
BHE12106836	E5474Hu	96T	$458		Add to Cart

Human Insulin-like Growth Factor 2 MRNA-binding Protein 3 - IGF2BP3 ELISA Kit

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