Human Growth Hormone Receptor

Mfr.No.

E6481Hu

Sensitivity

0.019ng/ml

Detection Range

0.05-10ng/ml

Reactivity

Human

Assay Duration

1h 30m

Assay Type

Sandwich

Alternative Names

GH receptor;GH-binding protein;GHBP;GHR;Growth hormone receptor;Growth hormone-binding protein;Serum-binding protein;Somatotropin receptor

Molecular Weight

71500

Kit Components

Components	Quantity
Pre-coated ELISA Plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Precision

We measured random samples of E6481Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	4.4	0.13	2.8
Intra-Assay	2	18	2.9	0.19	6.6
Intra-Assay	3	18	1.6	0.11	6.9

Background

Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity). The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.

Protocol

These standard curves of E6481Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
6.4ng/ml	2.173	2.145	2.108
	2.116
3.2ng/ml	1.246	1.219	1.181
	1.191
1.6ng/ml	0.774	0.791	0.753
	0.807
0.8ng/ml	0.498	0.476	0.438
	0.453
0.4ng/ml	0.201	0.199	0.161
	0.196
0ng/ml	0.026	0.037	0
	0.049

Gene ID	2690
UniProt ID	P10912

Research Area	Signal Transduction; Cell Biology; Cancer

Storage	2-8°C

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SKU	Supplier No.	Size	Your price	Quantity
BHE12115650	E6481Hu	48T	$320		Add to Cart
BHE12115650	E6481Hu	96T	$458		Add to Cart

Human Growth Hormone Receptor - GHR ELISA Kit

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