Human Cc-Chemokine Receptor 5

Mfr.No.

E3600Hu

Description

This sandwich kit is for the accurate quantitative detection of human CC-Chemokine Receptor 5 (also known as CCR5) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates.

Alternative Names

C-C chemokine receptor type 5;C-C CKR-5;CC-CKR-5;CCR 5;CCR5;CCR-5;CD antigen CD195;CHEMR13;HIV-1 fusion coreceptor;

Reactivity

Human

Detection Range

5-2000ng/L

Sample Type

Serum, Plasma, Cell culture supernatants

Assay Type

Sandwich

Assay Duration

1h 30m

Molecular Weight

40524

Kit Components

Components	Quantity
Pre-coated ELISA Plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Sensitivity

2.61ng/L

Background

Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor (PubMed: 30713770). (Microbial infection) Acts as a coreceptor (CD4 being the primary receptor) of human immunodeficiency virus-1/HIV-1.

Gene ID	1234
UniProt ID	P51681
Antigen	CCR5

Research Area

Others

Protocol

These standard curves of E3600Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
1200ng/L	2.123	2.129	2.103
	2.135
600ng/L	1.218	1.229	1.203
	1.241
300ng/L	0.559	0.651	0.625
	0.743
150ng/L	0.349	0.398	0.372
	0.446
75ng/L	0.17	0.169	0.143
	0.167
0ng/L	0.014	0.026	0
	0.038

Precision

We measured random samples of E3600Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	366.5	16.93	4.6
Intra-Assay	2	18	767.2	24.83	3.2
Intra-Assay	3	18	270.7	15.52	5.7

Storage	2-8°C

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SKU	Supplier No.	Size	Your price	Quantity
BHE12105078	E3600Hu	48T	$320		Add to Cart
BHE12105078	E3600Hu	96T	$458		Add to Cart

Human Cc-Chemokine Receptor 5 - CCR-5 ELISA Kit

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