Human C-C Chemokine Receptor Type 3

Mfr.No.

E4998Hu

Alternative Names

C C CKR3;C-C chemokine receptor type 3;C-C CKR-3;CC-CKR-3;CCR 3;CCR3;CCR-3;CD antigen CD193;CKR 3;CKR3;Eosinophil eotaxin receptor

Reactivity

Human

Detection Range

30-9000ng/L

Sample Type

Serum, Plasma, Cell culture supernatants

Assay Type

Sandwich

Assay Duration

1h 30m

Molecular Weight

41044

Kit Components

Components	Quantity
Pre-coated ELISA Plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Sensitivity

14.01ng/L

Background

Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15 (PubMed: 7622448, PubMed: 8642344, PubMed: 8676064). Subsequently transduces a signal by increasing the intracellular calcium ions level (PubMed: 8676064). In addition acts as a possible functional receptor for NARS1 (PubMed: 30171954). (Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection.

Gene ID	1232
UniProt ID	P51677
Antigen	CCR3

Research Area

Others

Protocol

These standard curves of E4998Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
4800ng/L	2.278	2.181	2.139
	2.085
2400ng/L	1.466	1.499	1.457
	1.533
1200ng/L	0.756	0.846	0.804
	0.936
600ng/L	0.536	0.47	0.427
	0.403
300ng/L	0.232	0.253	0.21
	0.273
0ng/L	0.035	0.043	0
	0.05

Precision

We measured random samples of E4998Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	3326.9	159.53	4.8
Intra-Assay	2	18	1123.9	53.37	4.7
Intra-Assay	3	18	673.7	33.32	4.9

Storage	2-8°C

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SKU	Supplier No.	Size	Your price	Quantity
BHE12106361	E4998Hu	48T	$320		Add to Cart
BHE12106361	E4998Hu	96T	$458		Add to Cart

Human C-C Chemokine Receptor Type 3 - CCR3 ELISA Kit

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