Human 28S ribosomal protein S22, mitochondrial (MRPS22) ELISA Kit

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPS22 encodes a 28S subunit protein, mitochondrial ribosomal protein S22 that does not seem to...

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPS22 encodes a 28S subunit protein, mitochondrial ribosomal protein S22 that does not seem to have a counterpart in prokaryotic and fungal-mitochondrial ribosomes. MRPS22 lies telomeric of and is transcribed in the opposite direction from the forkhead box L2 gene. A pseudogene corresponding to MRPS22 is found on chromosome Xq.