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Yme1l1-Flox

SKU : BHAM00342

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	TBD
Description	Model Description: These mice carry loxP sites flanking target exons of Yme1l1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Yme1l1 gene. Official Symbol: Yme1l1 NCBI ID: 27377 MGI ID: 1351651 Ensembl ID: ENSMUSG00000026775 Pubmed: Yme1l1 Human Ortholog: YME1L1
Nomenclature	C57BL/6JSmoc-Yme1l1^{em1(flox)Smoc}
Exon	Exon s
Disease	Dilated Cardiomyopathy
Disease	Cardio-metabolic Disease
KI/KO Gene	Yme1l1
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Myh6-cre mice.
Synonyms	Ftsh, FtsH1

Reference	MGI:5762957 Wai T, Garcia-Prieto J, Baker MJ, Merkwirth C, Benit P, Rustin P, Ruperez FJ, Barbas C, Ibanez B, Langer T, Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice. Science. 2015 Dec 4;350(6265):aad0116

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