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Shank3-KO

SKU : BHAM00292

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	TBD
Description	Model Description: Exon 4-9 of Shank3 gene was deleted to generate Shank3 knockout mice. Official Symbol: Shank3 NCBI ID: 58234 MGI ID: 1930016 Ensembl ID: ENSMUSG00000022623 Pubmed: Shank3 Human Ortholog: SHANK3
Nomenclature	C57BL/6JSmoc-Shank3^em1Smoc
Exon	Exon 4-9
Disease	Autism Spectrum Disorder
Disease	Nervous System Disease
KI/KO Gene	Shank3
Synonyms	Spank-2, proSAP2, AI841104

Reference	Bozdagi O, Sakurai T, Papapetrou D, Wang X, Dickstein DL, Takahashi N, Kajiwara Y, Yang M, Katz AM, Scattoni ML, Harris MJ, Saxena R, Silverman JL, Crawley JN, Zhou Q, Hof PR, Buxbaum JD, Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication. Mol Autism. 2010;1(1):15

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