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Scarb2-KO

SKU : BHAM00296

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-KO-201201
Description	Model Description: Exon 2 of Scarb2 gene was deleted to generate Scarb2 knockout mice. Official Symbol: Scarb2 NCBI ID: 12492 MGI ID: 1196458 Ensembl ID: ENSMUSG00000029426 Pubmed: Scarb2 Human Ortholog: SCARB2
Nomenclature	C57BL/6JSmoc-Scarb2^em1Smoc
Exon	Exon 2
Disease	Progressive Myoclonus Epilepsy
Disease	Nervous System Disease
KI/KO Gene	Scarb2
Synonyms	LGP85, Cd36l2, LIMP-2, MLGP85, LIMP II, 9330185J12Rik

Reference	MGI:5707775 Rothaug M, Zunke F, Mazzulli JR, Schweizer M, Altmeppen H, Lullmann-Rauch R, Kallemeijn WW, Gaspar P, Aerts JM, Glatzel M, Saftig P, Krainc D, Schwake M, Blanz J, LIMP-2 expression is critical for beta-glucocerebrosidase activity and alpha-synuclein clearance. Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15573-8

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