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Home / Animal Model / Disease Mice

R26-CAG-LSL-hEGFR*L858R/T790M/C797S-IRES-Luc-2A-tdTomato

SKU : BHAM00251

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-KI-190067
Description	Model Description: These mice harbor a CAG-LSL-EGFR (L858R-T790M-C797S)-IRES-luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination. Official Symbol: Gt(ROSA)26Sor NCBI ID: 14910 MGI ID: 104735 Ensembl ID: ENSMUSG00000086429 Pubmed: Gt(ROSA)26Sor Human Ortholog: On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Nomenclature	C57BL/6JSmoc-Gt(ROSA)26Sor^{em1(CAG-LSL-EGFR (L858R-T790M-C797S)-IRES-luciferase-2A-tdTomato)Smoc}
Application	Cancer Research
KI/KO Gene	Gt(ROSA)26Sor
Synonyms	R26,ROSA26,AV258896,Gtrgeo26,Gtrosa26,Thumpd3as1

Reference	MGI:2653988

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