Model Description: Exon 2-4 of Pts gene was deleted to generate Pts knockout mice.
Official Symbol: Pts
NCBI ID: 19286
MGI ID: 1338783
Ensembl ID: ENSMUSG00000032067
Pubmed: Pts
Human Ortholog: PTS
Nomenclature
C57BL/6JSmoc-Ptsem1Smoc
Exon
Exon 2-4
Application
Studies On Metabolism And Folic Acid Biosynthesis
Disease
Bh4-Deficient Hyperphenylalaninemia A
Disease
Rare Disease
KI/KO Gene
Pts
Synonyms
PTPS
Reference
Sumi-Ichinose C, Urano F, Kuroda R, Ohye T, Kojima M, Tazawa M, Shiraishi H, Hagino Y, Nagatsu T, Nomura T, Ichinose H, Catecholamines and serotonin are differently regulated by tetrahydrobiopterin. A study from 6-pyruvoyltetrahydropterin synthase knockout mice. J Biol Chem. 2001 Nov 2;276(44):41150-60