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Ppp1r13l-KO

SKU : BHAM00231

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-KO-201327
Description	Model Description: Exon 4-7 of Ppp1r13l gene was deleted to generate Ppp1r13l knockout mice. Official Symbol: Ppp1r13l NCBI ID: 333654 MGI ID: 3525053 Ensembl ID: ENSMUSG00000040734 Pubmed: Ppp1r13l
Nomenclature	C57BL/6JSmoc-Ppp1r13l^em1Smoc
Exon	Exon 4-7
Disease	Arrhythmogenic Right Ventricular Cardiomyopathy
Disease	Cardio-metabolic Disease
KI/KO Gene	Ppp1r13l
Synonyms	wa3, IASPP, Nkip1, AV260376

Reference	MGI:5284901 Notari M, Hu Y, Sutendra G, Dedeic Z, Lu M, Dupays L, Yavari A, Carr CA, Zhong S, Opel A, Tinker A, Clarke K, Watkins H, Ferguson DJ, Kelsell DP, de Noronha S, Sheppard MN, Hollinshead M, Mohun TJ, Lu X, iASPP, a previously unidentified regulator of desmosomes, prevents arrhythmogenic right ventricular cardiomyopathy (ARVC)-induced sudden death. Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):E973-81

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