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Pomc-KO

SKU : BHAM00235

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-KO-190658
Description	Model Description: Exon 2-3 of Pomc gene was deleted to generate Pomc knockout mice. Official Symbol: Pomc NCBI ID: 18976 MGI ID: 97742 Ensembl ID: ENSMUSG00000020660 Pubmed: Pomc Human Ortholog: PMOC
Exon	Exon 2-3
Application	Early Onset Obesity,Adrenal Insufficiency,And Red Hair Pigmentation
Disease	Obesity
KI/KO Gene	Pomc
Synonyms	BE, Npp, ACTH, Clip, Pomc1, Pomc-1, Beta-LPH, alphaMSH, beta-MSH, Gamma-LPH, alpha-MSH, gamma-MSH

Reference	MGI:6389045 Challis BG, Coll AP, Yeo GS, Pinnock SB, Dickson SL, Thresher RR, Dixon J, Zahn D, Rochford JJ, White A, Oliver RL, Millington G, Aparicio SA, Colledge WH, Russ AP, Carlton MB, O'Rahilly S, Mice lacking pro-opiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY(3-36). Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4695-700

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