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Pdlim5-Flox

SKU : BHAM00230

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	TBD
Description	Model Description: These mice carry loxP sites flanking target exons of Pdlim5 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Pdlim5 gene. Official Symbol: Pdlim5 NCBI ID: 56376 MGI ID: 1927489 Ensembl ID: ENSMUSG00000028273 Pubmed: Pdlim5 Human Ortholog: PDLIM5
Nomenclature	C57BL/6JSmoc-Pdlim5^{em1(flox)Smoc}
Exon	Exon s
Disease	Dilated Cardiomyopathy
Disease	Cardio-metabolic Disease
KI/KO Gene	Pdlim5
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Tnnt2-cre mice.
Synonyms	Enh, LIM, Enh1, Enh2, Enh3, C87059, AI987914, 1110001A05Rik

Reference	MGI:5284902 Cheng H, Kimura K, Peter AK, Cui L, Ouyang K, Shen T, Liu Y, Gu Y, Dalton ND, Evans SM, Knowlton KU, Peterson KL, Chen J, Loss of enigma homolog protein results in dilated cardiomyopathy. Circ Res. 2010 Aug 6;107(3):348-56

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