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Nexn-Flox

SKU : BHAM00195

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	TBD
Description	Model Description: These mice carry loxP sites flanking target exons of Nexn gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Nexn gene. Official Symbol: Nexn NCBI ID: 68810 MGI ID: 1916060 Ensembl ID: ENSMUSG00000039103 Pubmed: Nexn Human Ortholog: NEXN
Nomenclature	C57BL/6JSmoc-Nexn^{em1(flox)Smoc}
Exon	Exon s
Disease	Dilated Cardiomyopathy 1Cc
Disease	Cardio-metabolic Disease
KI/KO Gene	Nexn
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Tnnt2-cre mice.
Synonyms	NELIN, AA553326, 1110046H09Rik

Reference	MGI:6514898 Liu C, Spinozzi S, Chen JY, Fang X, Feng W, Perkins G, Cattaneo P, Guimaraes-Camboa N, Dalton ND, Peterson KL, Wu T, Ouyang K, Fu XD, Evans SM, Chen J, Nexilin Is a New Component of Junctional Membrane Complexes Required for Cardiac T-Tubule Formation. Circulation. 2019 Jul 2;140(1):55-66

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