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Ncstn-Flox

SKU : BHAM00199

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	TBD
Description	Model Description: These mice carry loxP sites flanking target exons of Ncstn gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ncstn gene. Official Symbol: Ncstn NCBI ID: 59287 MGI ID: 1891700 Ensembl ID: ENSMUSG00000003458 Pubmed: Ncstn Human Ortholog: NCSTN
Nomenclature	C57BL/6JSmoc-Ncstn^{em1(flox)Smoc}
Exon	Exon s
Disease	Chronic Myeloid Leukemia
Disease	Nervous System Disease
KI/KO Gene	Ncstn
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with VAV1-cre mice.
Synonyms	Nct, Aph2, AA727311, D1Dau13e, Kiaa0253, mKIAA0253, 9430068N19Rik

Reference	MGI:5751579 Klinakis A, Lobry C, Abdel-Wahab O, Oh P, Haeno H, Buonamici S, van De Walle I, Cathelin S, Trimarchi T, Araldi E, Liu C, Ibrahim S, Beran M, Zavadil J, Efstratiadis A, Taghon T, Michor F, Levine RL, Aifantis I, A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia. Nature. 2011 May 12;473(7346):230-3

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