Model Description: These mice carry loxP sites flanking target exons of Ncoa6 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ncoa6 gene.
Official Symbol: Ncoa6
NCBI ID: 56406
MGI ID: 1929915
Ensembl ID: ENSMUSG00000038369
Pubmed: Ncoa6
Human Ortholog: NCOA6
Nomenclature
C57BL/6JSmoc-Ncoa6em1(flox)Smoc
Exon
Exon s
Disease
Dilated Cardiomyopathy
Disease
Cardio-metabolic Disease
KI/KO Gene
Ncoa6
Notes
Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Myh6-cre mice.
Roh JI, Cheong C, Sung YH, Lee J, Oh J, Lee BS, Lee JE, Gho YS, Kim DK, Park CB, Lee JH, Lee JW, Kang SM, Lee HW, Perturbation of NCOA6 leads to dilated cardiomyopathy. Cell Rep. 2014 Aug 21;8(4):991-8