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Met-Flox

SKU : BHAM00187

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-CKO-200328
Description	Model Description: These mice carry loxP sites flanking exon 16 of Met gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Met gene. Official Symbol: Met NCBI ID: 17295 MGI ID: 96969 Ensembl ID: ENSMUSG00000009376 Pubmed: Met Human Ortholog: MET
Nomenclature	C57BL/6JSmoc-Met^{em1(flox)Smoc}
Exon	Exon 16
Disease	Gilles De La Tourette Syndrome
Disease	Cardio-metabolic Disease
KI/KO Gene	Met
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Mi56i-cre mice.
Synonyms	HGF, HGFR, Par4, c-Met, AI838057

Reference	MGI:5756630 Martins GJ, Shahrokh M, Powell EM, Genetic disruption of Met signaling impairs GABAergic striatal development and cognition. Neuroscience. 2011 Mar 10;176:199-209

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