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Ldb3-Flox

SKU : BHAM00151

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	TBD
Description	Model Description: These mice carry loxP sites flanking target exons of Ldb3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ldb3 gene. Official Symbol: Ldb3 NCBI ID: 24131 MGI ID: 1344412 Ensembl ID: ENSMUSG00000021798 Pubmed: Ldb3 Human Ortholog: LDB3
Nomenclature	C57BL/6JSmoc-Ldb3^{em1(flox)Smoc}
Exon	Exon s
Disease	Dilated Cardiomyopathy 1C
Disease	Cardio-metabolic Disease
KI/KO Gene	Ldb3
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Myl2-Cre mice.
Synonyms	ZASP, PDLIM6, AW742271

Reference	Zheng M, Cheng H, Li X, Zhang J, Cui L, Ouyang K, Han L, Zhao T, Gu Y, Dalton ND, Bang ML, Peterson KL, Chen J, Cardiac-specific ablation of Cypher leads to a severe form of dilated cardiomyopathy with premature death. Hum Mol Genet. 2009 Feb 15;18(4):701-13

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