Model Description: These mice carry a p.C96Y mutation of Ins2 gene.
Official Symbol: Ins2
NCBI ID: 16334
MGI ID: 96573
Ensembl ID: ENSMUSG00000000215
Pubmed: Ins2
Human Ortholog: INS
Nomenclature
C57BL/6JSmoc-Ins2em3(C96Y)Smoc
Application
Diabetes Related.
Disease
Diabetes
KI/KO Gene
Ins2
Synonyms
Ins-2 InsII Mody Mody4
Reference
Yoshioka M, et al., A novel locus, Mody4, distal to D7Mit189 on chromosome 7 determines early-onset NIDDM in nonobese C57BL/6 (Akita) mutant mice. Diabetes. 1997 May;46(5):887-94