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Glul-Flox

SKU : BHAM00113

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-CKO-220528
Description	Model Description: These mice carry loxP sites flanking exon 4-7 of Glul When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Glul gene. Official Symbol: Glul NCBI ID: 14645 MGI ID: 95739 Ensembl ID: ENSMUSG00000026473 Pubmed: Glul Human Ortholog: GLUL
Nomenclature	C57BL/6JSmoc-Glul^{em(flox)/Smoc}
Exon	Exon 4-7
Disease	Temporal Lobe Epilepsy
Disease	Nervous System Disease
KI/KO Gene	Glul
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Emx1-Cre mice.
Synonyms	GS, Glns

Reference	MGI:3664276 Zhou Y, Dhaher R, Parent M, Hu QX, Hassel B, Yee SP, Hyder F, Gruenbaum SE, Eid T, Danbolt NC, Selective deletion of glutamine synthetase in the mouse cerebral cortex induces glial dysfunction and vascular impairment that precede epilepsy and neurodegeneration. Neurochem Int. 2019 Feb;123:22-33

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