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Eif4ebp2-KO

SKU : BHAM00086

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-KO-191121
Description	Model Description: Exon 3-4 of Eif4ebp2 gene was deleted to generate Eif4ebp2 knockout mice. Official Symbol: Eif4ebp2 NCBI ID: 13688 MGI ID: 109198 Ensembl ID: ENSMUSG00000020091 Pubmed: Eif4ebp2 Human Ortholog: EIF4EBP2
Nomenclature	C57BL/6JSmoc-Eif4Ebp2^em1Smoc
Exon	Exon 3-4
Application	Cell Proliferation And Differentiation, Viral Infection, Nervous System, Synaptic Transmission, Autism, Muscle Homeostasis
Disease	Autism Spectrum Disorder
Disease	Nervous System Disease
KI/KO Gene	Eif4ebp2
Synonyms	4E-BP2, PHAS-II, AA792569, BC010348, 2810011I19Rik

Reference	MGI:3719798 Gkogkas CG, Khoutorsky A, Ran I, Rampakakis E, Nevarko T, Weatherill DB, Vasuta C, Yee S, Truitt M, Dallaire P, Major F, Lasko P, Ruggero D, Nader K, Lacaille JC, Sonenberg N, Autism-related deficits via dysregulated eIF4E-dependent translational control. Nature. 2013 Jan 17;493(7432):371-7

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