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Cox10-Flox

SKU : BHAM00052

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	TBD
Description	Model Description: These mice carry loxP sites flanking target exons of Cox10 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Cox10 gene. Official Symbol: Cox10 NCBI ID: 70383 MGI ID: 1917633 Ensembl ID: ENSMUSG00000042148 Pubmed: Cox10 Human Ortholog: COX10
Nomenclature	C57BL/6JSmoc-Cox10^{em1(flox)Smoc}
Exon	Exon s
Disease	Parkinson's Disease
Disease	Nervous System Disease
KI/KO Gene	Cox10
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Slc6a3-cre mice.
Synonyms	AU042636, 2410004F01Rik

Reference	MGI:5465105 Pinto M, Nissanka N, Peralta S, Brambilla R, Diaz F, Moraes CT, Pioglitazone ameliorates the phenotype of a novel Parkinson's disease mouse model by reducing neuroinflammation. Mol Neurodegener. 2016;11:25

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