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Cldn16-KO

SKU : BHAM00055

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-KO-200632
Description	Model Description: Exon 2 of Cldn16 gene was deleted to generate Cldn16 knockout mice. Official Symbol: Cldn16 NCBI ID: 114141 MGI ID: 2148742 Ensembl ID: ENSMUSG00000038148 Pubmed: Cldn16 Human Ortholog: CLDN16
Nomenclature	C57BL/6JSmoc-Cldn16^em1Smoc
Exon	Exon 2
Application	Sertoli-Sertoli Cell Junction Dynamics And Cell Junction Organization Related Research
Disease	Renal Hypomagnesemia 3
Disease	Rare Disease
KI/KO Gene	Cldn16
Synonyms	PCLN1, claudin-16

Reference	MGI:5295268 Will C, Breiderhoff T, Thumfart J, Stuiver M, Kopplin K, Sommer K, Gunzel D, Querfeld U, Meij IC, Shan Q, Bleich M, Willnow TE, Muller D, Targeted deletion of murine Cldn16 identifies extra- and intrarenal compensatory mechanisms of Ca2+ and Mg2+ wasting. Am J Physiol Renal Physiol. 2010 May;298(5):F1152-61

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