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Cdyl-Flox

SKU : BHAM00041

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	TBD
Description	Model Description: These mice carry loxP sites flanking target exons of Cdyl gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Cdyl gene. Official Symbol: Cdyl NCBI ID: 12593 MGI ID: 1339956 Ensembl ID: ENSMUSG00000059288 Pubmed: Cdyl Human Ortholog: CDYL
Nomenclature	C57BL/6JSmoc-Cdyl^{em1(flox)Smoc}
Exon	Exon s
Disease	Epilepsy
Disease	Nervous System Disease
KI/KO Gene	Cdyl
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Emx1-Cre mice.
Synonyms	AI325931

Reference	Alison M. Muir, Yinshi Ren, Delana Hopkins Butz, Nicholas A. Davis, Robert D. Blank, David E. Birk, Se-Jin Lee, David Rowe, Jian Q. Feng, Daniel S. Greenspan, Induced ablation of Bmp1 and Tll1 produces osteogenesis imperfecta in mice. Hum Mol Genet . 2014 Jun 15;23(12):3085-101. Qin R, Cao S, Lyu T, Qi C, Zhang W, Wang Y, CDYL Deficiency Disrupts Neuronal Migration and Increases Susceptibility to Epilepsy. Cell Rep. 2017 Jan 10;18(2):380-390

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