Model Description: Exon 3-8 of Agxt gene was deleted to generate Agxt knockout mice.
Official Symbol: Agxt
NCBI ID: 11611
MGI ID: 1329033
Ensembl ID: ENSMUSG00000026272
Pubmed: Agxt
Human Ortholog: AGXT
Nomenclature
C57BL/6JSmoc-Agxtem1Smoc
Exon
Exon 3-8
Disease
Primary Hyperoxaluria Type 1
Disease
Rare Disease
KI/KO Gene
Agxt
Synonyms
AGT, SPT, Agt1, Agxt1
Reference
Salido EC, Li XM, Lu Y, Wang X, Santana A, Roy-Chowdhury N, Torres A, Shapiro LJ, Roy-Chowdhury J, Alanine-glyoxylate aminotransferase-deficient mice, a model for primary hyperoxaluria that responds to adenoviral gene transfer. Proc Natl Acad Sci U S A. 2006 Nov 28;103(48):18249-54