DENARASE® and DENARASE® ELISA Kit

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DENARASE® and DENARASE® ELISA Kit

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Accelerate the Manufacturing of Gene and Cell Therapies with GMP Enzymes from c-LEcta

"The manufacturing of gene and cell therapies required highest quality, innovative and cost-effecient enzymes - this is our focus at c-LEcta"

Dr. Raphael Gübeli
Head of Markeiting, c-LEcta GmbH

The description provided outlines an enzyme, likely DENARASE^®, used in bioprocessing for enzymatic DNA removal. It exhibits high activity towards a wide range of DNA/RNA substrates. The manufacturing process is devoid of animal-derived materials and antibiotics, utilizing an endotoxin-free expression host. This enzyme boasts high purity of at least 99% and is produced under Good Manufacturing Practice (GMP) conditions. Additionally, comprehensive technical support is offered by a team of experts to assist in integrating this enzyme within bioprocessing workflows, making it a valuable asset for professionals in the biopharmaceutical domain, particularly in viral vector production or gene therapy fields.

About DENARASE^®

The details provided outline a method for the quantitative analysis of residual Serratia marcescens endonucleases, employing a monoclonal antibody to achieve unmatched accuracy and reproducibility. This approach is time-saving, offering a lowest detection limit of 4 pg/mL and a quantification limit of 12 pg/mL. It boasts a broad working range of approximately 32 pg/mL to 1000 pg/mL at OD450. Additionally, a team of experts is available to provide comprehensive technical support, enhancing the method's ease of implementation and troubleshooting, making it a valuable tool for precise quantification in bioprocessing or other related applications.

About DENARASEE^® ELISA Kit

Order DENARASE^® and DENARASE^® ELISA Kit now!

DENARASE^® R&D-grade

Products for use in research and development

This enzyme is tailored for process development in biological realms like viral vectors and vaccines, proficiently cleaving all DNA and RNA forms to streamline downstream processes.

Purity: ≥ 99%
Activity: > 250 U/µl

Formulation: Comes in a buffered aqueous glycerol solution
Storage Temperature: -20°C
Estimated Delivery: 1-2 weeks, region-dependent

Compliance: Aligns with ISO 9001 standards
Manufacturing: Void of animal-derived materials and antibiotics
Dosage: Application-dependent, ranging between 10 – 60 U/ml

Pricing: Net price exclusive of VAT and shipping charges

100KU 500KU 1000KU 5000KU

DENARASE® GMP-grade

GMP products for biopharmaceutical manufacturing

For the GMP manufacturing of biological entities like viral vectors and vaccines, this enzyme effectively diminishes all forms of DNA and RNA, facilitating a more streamlined, efficient downstream process.

Purity: ≥ 99%
Activity: > 250 U/µl

Formulation: Buffered aqueous glycerol solution
Storage Temperature: -20°C
Estimated Delivery: 1-2 weeks (region-variable)

Production Standards: Adheres to EU GMP conditions
Manufacturing: Excludes the use of animal-derived materials and antibiotics
Regulatory Support: Dedicated assistance for US-market pharmaceutical product approvals via a proprietary US FDA Drug Master File

Pricing: Net price exclusing VAT and shipping charges

1 MU, GMP 5 MU, GMP

ELISA Kit for DENARASE® and Benzonase*

For carrying out quantitative analysis of residual Serratia marcescens endonucleases in process samples, this kit is equipped with a pre-coated micro test plate along with ready-to-use reagents. It offers a capacity of 480 measurements per kit. The estimated delivery timeframe is 1-2 weeks, varying by region. Pricing is net, exclusive of VAT and shipping charges.

*Benzonase Nuclease is a registered trademark of Merck KGaA

Biohippo Inc. Partners with c-LEcta

Elevating the DENARASE® Supply Chain in the USA

Difference Between Benzonase and DENARASE®
Benzonase and DENARASE® are instrumental nucleases utilized extensively in molecular biology and biopharmaceutical domains.

Harnessing the Power of DENARASE® in AAV Production
DENARASE® is engineered by c-LEcta for high activity, making it an exceptional choice for degrading host-cell DNA during AAV production.

Get your free sample DENARASE^®!

New customers from the pharmaceutical industry can request a free 25 kU sample for first lab trials.

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DENARASE®GMP-grade

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DENARASE® ELISA Kit

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