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Home / Primary Antibodies

Cyclin D1 Antibody / CCND1

SKU : BHA17111750

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NSJ Bioreagents

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Mfr.No.	V2365PE
Clonality	Monoclonal
Description	This antibody recognizes a protein of 36kDa, identified as Cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression. The antibody is useful in identifying mantle cell lymphomas (Cyclin D1 positive) from CLL/SLL and follicular lymphomas (Cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
Formulation	500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Host	Mouse
Immunogen Region	Human recombinant full length Cyclin D1 protein was used as the immunogen.
Isotype	IgG2a,kappa
Predicted Reactivity	Human, Monkey, Mouse and Rat. Other species not known.
Reactivity	Human, Monkey, Mouse, Rat
Recombinant	No
Subcellular Location	Nuclear

Gene Id	595
Clone No	CCND1/809

Concentration	0.1 mg/ml
Format	PE Conjugate
Purification	Protein G affinity chromatography
Storage	Store the Cyclin D1 antibody at 2-8°C. Conjugate is light sensitive, store in the dark.

Applications	FACS, IF
Dilution	Flow Cytometry: 5ul/test/million cells or 5ul/test/100ul of whole blood,Immunofluorescence: 1:50-1:100 for 30 minutes at RT

Product Manual	Data Sheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA17111750	V2365PE	100 Tests	$499		Add to Cart

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