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Home / Primary Antibodies / Conjugated Primary Antibodies

PKD1L1 Antibody, FITC conjugated

SKU : BHA10528534

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA823467LC01HU
Alternative Names	Polycystic kidney disease protein 1-like 1 (PC1-like 1 protein) (Polycystin-1L1), PKD1L1
Categories	Primary Antibodies
Clonality	polyclonal
Description	Component of a ciliary calcium channel that controls calcium concentration within primary cilia without affecting cytoplasmic calcium concentration. Forms a heterodimer with PKD2L1 in primary cilia and forms a calcium-permeant ciliary channel that regulates sonic hedgehog/SHH signaling and GLI2 transcription. Does not constitute the pore-forming subunit. Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD2 in cilia to facilitate flow detection in left/right patterning.
Host	Rabbit
Immunogen	Recombinant Human Polycystic kidney disease protein 1-like 1 protein (921-1164AA)
Involvement In Disease	Heterotaxy, visceral, 8, autosomal (HTX8)
Isotype	IgG
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Component of a ciliary calcium channel that controls calcium concentration within primary cilia without affecting cytoplasmic calcium concentration. Forms a heterodimer with PKD2L1 in primary cilia and forms a calcium-permeant ciliary channel that regulates sonic hedgehog/SHH signaling and GLI2 transcription. Does not constitute the pore-forming subunit. Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD2 in cilia to facilitate flow detection in left/right patterning.
Species	Homo Sapiens (Human)
Subcellular Location	Cell projection, cilium membrane, Multi-pass membrane protein

Uniprot	Q8TDX9
Database Links	HGNC:18053 OMIM:609721 KEGG:hsa:168507 STRING:9606.ENSP00000289672 UniGene:Hs.195979
Function	Component of a ciliary calcium channel that controls calcium concentration within primary cilia without affecting cytoplasmic calcium concentration. Forms a heterodimer with PKD2L1 in primary cilia and forms a calcium-permeant ciliary channel that regulates sonic hedgehog/SHH signaling and GLI2 transcription. Does not constitute the pore-forming subunit. Also involved in left/right axis specification downstream of nodal flow
Protein Families	Polycystin family
Research Area	Others
Tissue Specificity	Detected in testis and in fetal and adult heart.

Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form	Liquid
Format	Liquid
Purification	>95%, Protein G purified
Purity	>95%,Protein G purified
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Applications	ELISA
Description	ELISA
Tested Application	ELISA

Datasheet
ELISA Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10528534	CSB-PA823467LC01HU	100ug	$299		Add to Cart
BHA10528534	CSB-PA823467LC01HU	50ug	$166		Add to Cart

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