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Home / Primary Antibodies / Conjugated Primary Antibodies

MCUB Antibody, HRP conjugated

SKU : BHA10516576

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA873671LB01HU
Alternative Names	Calcium uniporter regulatory subunit MCUb, mitochondrial (MCUb) (Coiled-coil domain-containing protein 109B), MCUB, CCDC109B
Categories	Primary Antibodies
Clonality	polyclonal
Description	Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
Host	Rabbit
Immunogen	Recombinant Human Calcium uniporter regulatory subunit MCUb, mitochondrial protein (89-219AA)
Isotype	IgG
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
Species	Homo Sapiens (Human)
Subcellular Location	Mitochondrion inner membrane, Multi-pass membrane protein

Uniprot	Q9NWR8
Database Links	HGNC:26076 KEGG:hsa:55013 STRING:9606.ENSP00000378145 UniGene:Hs.234149
Function	Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
Protein Families	MCU (TC 1.A.77) family
Research Area	Others

Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form	Liquid
Format	Liquid
Purification	Antigen Affinity Purified
Purity	>95%,Protein G purified
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Applications	ELISA
Description	ELISA
Tested Application	ELISA

Datasheet
ELISA Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10516576	CSB-PA873671LB01HU	100ug	$299		Add to Cart
BHA10516576	CSB-PA873671LB01HU	50ug	$166		Add to Cart

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